BPC-157 in 2026: FDA List Status, Sequence, Molecular Weight, CAS and Acetate vs TFA Salt Form

As of September 24, 2026, BPC-157 is not in the FDA's current Category 2 table: the FDA compounding page that holds the Category 2 table (content current as of April 22, 2026) lists BPC-157 in its separate table of "bulk drug substances nominated but withdrawn". BPC-157 had been added to Category 2 under the 503A interim policy on September 29, 2023. Chemically, BPC-157 is the synthetic 15-residue peptide GEPPPGKPADDAGLV, formula C62H98N16O22, molecular weight 1419.53 g/mol, CAS 137525-51-0, PubChem CID 9941957 and UNII 8ED8NXK95P. This page puts the dated list status, the verified identity record, the acetate and trifluoroacetate (TFA) salt forms and the calculated mass-spectrometry ions for BPC-157 in one place.

What is the FDA status of BPC-157 in 2026?

BPC-157 appears in the FDA table headed "bulk drug substances nominated but withdrawn", which the FDA describes as substances previously in Category 2 of the interim policies whose nominations were withdrawn by the nominators. The page carries the date "content current as of 04/22/2026", and it was checked again on September 24, 2026. BPC-157 is therefore not shown in the page's current Category 2 table.

The row-by-row record for every listed compound, with the name each FDA entry uses, is kept in the FDA Category 2 peptides 2026 ledger. Always read the content-current date on the FDA page itself before relying on any summary, including this one.

What do the 503A and 503B lists cover?

The 503A and 503B category lists govern which bulk substances compounding pharmacies (503A) and outsourcing facilities (503B) may use in compounding. They are compounding lists, not registries of chemical identity, and the FDA entry for BPC-157 carries no CAS number or formula. Pepta Labs lists BPC-157 as a laboratory reference material, labelled for research use only and not for human or animal use, and ships to US addresses only. The wider labelling and list picture for all listed compounds is in peptide legal status 2026, and the basics of what a research peptide listing is are in what are research peptides.

What are the BPC-157 sequence, formula, molecular weight and CAS number?

BPC-157 is H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH, written GEPPPGKPADDAGLV in one-letter code, with the molecular formula C62H98N16O22 and a molecular weight of 1419.53 g/mol. The values below are the Pepta Labs listing values; the registry numbers and formula match PubChem CID 9941957 and FDA GSRS UNII 8ED8NXK95P, and PubChem gives the same molecular weight rounded to 1419.5 g/mol.

Which amino acids make up GEPPPGKPADDAGLV?

BPC-157 contains eight different amino acids, and proline is the most frequent: four of the fifteen residues are proline, three of them consecutive at positions 3 to 5. The composition below is counted from the listed sequence.

The formula can be checked by hand. The fifteen free amino acids sum to C62H126N16O36; forming fourteen peptide bonds removes fourteen molecules of water (H28O14), leaving C62H98N16O22. The "H-" and "-OH" in the three-letter sequence mark the unmodified termini. How one-letter and three-letter codes and terminal groups are written is explained in peptide sequence notation.

Which CAS number identifies BPC-157?

CAS Registry Number 137525-51-0 identifies the free 15-residue peptide GEPPPGKPADDAGLV, the same entity recorded as PubChem CID 9941957 and UNII 8ED8NXK95P. A salt can be registered under its own number, so a certificate or listing that quotes a different CAS number for "BPC-157" should also state the salt form, formula and mass it refers to. When two records disagree, match the formula C62H98N16O22 and the mass 1419.53 g/mol first, because a formula and mass follow directly from the sequence while a registry number can be mistyped or copied between records. How to resolve a mismatch is covered in peptide registry discrepancies, and the same fields for every listed compound are in research peptide CAS numbers and molecular weights.

Which counter-ion salts is BPC-157 listed as, acetate or TFA?

Synthetic BPC-157 is normally isolated as an acetate or a trifluoroacetate salt, and the Pepta Labs listing records the salt form as "typically supplied as acetate or trifluoroacetate salt". The counter-ion is an anion that pairs with a protonated amine on the peptide. BPC-157 has two such basic sites, the free N-terminal amine and the lysine side chain at position 7, and no arginine or histidine, so an idealized salt carries at most two counter-ions per peptide molecule.

Trifluoroacetate comes from the trifluoroacetic acid used in reversed-phase purification, so it is the default salt of a peptide purified that way. The acetate salt is made by an extra exchange step after purification. Either way the sequence, the formula of the peptide and the mass the spectrometer reports stay the same; only the solid in the vial differs. Pepta Labs does not list BPC-157 as an arginate salt.

The salt rows add 60.05 g/mol per acetic acid and 114.02 g/mol per trifluoroacetic acid to the listed 1419.53 g/mol. They describe idealized stoichiometric salts, not the measured composition of any vial. The quantity on a Pepta Labs label is the supplier-stated nominal quantity of the lyophilized solid, and net peptide content is not reported on the listing. Why counter-ion and residual water make the gross solid heavier than the peptide alone is explained in TFA vs acetate and net peptide content and how net peptide content is determined.

Which masses should a BPC-157 mass spectrum show?

A positive-mode electrospray spectrum of BPC-157 should show the protonated free peptide, most often as [M+2H]²⁺ near m/z 710.4 and [M+H]⁺ near m/z 1419.7 (monoisotopic, calculated). Acetate and trifluoroacetate separate from the peptide on ionization, so the same ions are expected whichever salt was supplied. The values below are calculated, not measured: monoisotopic values from the formula C62H98N16O22 (C 12.000000, H 1.0078250, N 14.0030740, O 15.9949146) and average values from the listed 1419.53 g/mol, each with a proton mass of 1.00728 Da.

Three checks make the numbers readable on a report:

• Monoisotopic or average. A high-resolution instrument reports monoisotopic masses (1418.70 Da for the neutral peptide); a deconvoluted low-resolution result or a certificate's "molecular weight" line is usually the average mass (1419.53 g/mol). The two differ by 0.83 Da, so compare like with like.
• Charge state from isotope spacing. Isotope peaks sit 1.0 m/z apart for a 1+ ion, 0.5 apart for a 2+ ion and about 0.33 apart for a 3+ ion. For C62H98N16O22 the calculated isotope pattern is led by the monoisotopic peak (100%), followed by M+1 at about 75% and M+2 at about 32%.
• Adducts are not impurities. A sodium adduct sits 21.98 units above [M+H]⁺ and a potassium adduct 37.96 units above it. Both are common in electrospray spectra and do not indicate a different compound.

What mass shifts point to a deletion sequence?

A peak below the expected mass by exactly one residue mass corresponds to a peptide missing that residue, the typical by-product of a solid-phase coupling step that did not go to completion. The shifts below are calculated monoisotopic residue masses for the residues BPC-157 contains.

BPC-157 has no methionine, cysteine or tryptophan, so the +16 Da oxidation peak that matters for methionine-containing peptides is not an expected feature of its spectrum. Intact-mass MS confirms composition, not order: any rearrangement of the same fifteen residues has the same formula and the same mass, and residue order is confirmed only by fragmentation (MS/MS) data, which a standard identity report does not always include. The same calculation for every listed compound whose identity record is verified is in the expected mass table, and HPLC vs mass spec explains what each instrument can and cannot show.

What does the BPC-157 analytical report cover?

The BPC-157 report covers two tests on a sampled production run: RP-HPLC purity, stated as the main peak's share of total peak area, and mass-spectrometry identity, stated as the observed mass against the expected mass. Purity by area percent is not a measure of how many milligrams of peptide are in a vial.

• What is tested: Independent third-party HPLC purity analysis and mass-spectrometry identity confirmation, commissioned through the purchasing group on a sampled production run from the source. Pepta Labs does not test in-house.
• How to get it: Sent by email on request, before you order if you want to see it first, through the report request form.
• Who is named on it: Because testing is commissioned by the purchasing group, the client field may name the group or source rather than Pepta Labs, and supplier-identifying fields are redacted.
• Labels: Vial labels identify the compound, quantity and research-use designation. They do not carry lot or batch numbers.
• Not claimed: Sterility, endotoxin or LAL, potency, pharmaceutical-grade, cGMP, contaminant-panel and vial fill-quantity testing are not claimed.

The report therefore describes the sampled production run, not an individual vial. A line-by-line walkthrough of the compound name, chromatogram, purity figure and observed mass is in how to verify a peptide COA.

Which BPC-157 listings are there, and how are sealed vials stored?

Pepta Labs lists BPC-157 10 mg from $44.38 and BPC-157 20 mg from $85.59, and the price per mg of both sizes, beside every other listing, is in the research peptide price per mg table. Each product page shows its current stock, its pack options and its reported RP-HPLC purity.

BPC-157 ships as a dry lyophilized powder at ambient temperature, with no cold pack. The listing directs refrigeration at 2-8 C on arrival or storage at -20 C for the long term, with sealed vials kept away from light and moisture. Dry-powder storage for every listed compound is covered in the peptide storage guide.

BPC-157 10 mg is also one of the two separate sealed vials in the Wolverine bundle; the bundle page shows its contents and price. Identity data for the other vial in that bundle is in the TB-500 guide.

Frequently asked questions

What is the molecular weight of BPC-157?

The average molecular weight of BPC-157 is 1419.53 g/mol, for the free peptide C62H98N16O22 (PubChem CID 9941957). Its monoisotopic mass, calculated from the same formula, is 1418.70 Da. Acetate or trifluoroacetate salts weigh more as solids, but the peptide's own molecular weight does not change.

What is the BPC-157 sequence?

BPC-157 is the 15-residue linear peptide H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH, written GEPPPGKPADDAGLV in one-letter code. It has a free N-terminal amine and a free C-terminal carboxylic acid, and four of its fifteen residues are proline.

Which CAS number identifies BPC-157?

CAS 137525-51-0 identifies BPC-157 as the free peptide GEPPPGKPADDAGLV (C62H98N16O22, 1419.53 g/mol). The same entity is PubChem CID 9941957 and UNII 8ED8NXK95P in the FDA Global Substance Registration System.

Is BPC-157 supplied as an acetate or a TFA salt?

Synthetic BPC-157 is normally isolated as either an acetate or a trifluoroacetate (TFA) salt, and the Pepta Labs listing records it as typically supplied as one of the two. BPC-157 has two basic sites, so an idealized salt carries at most two counter-ions; the salt form does not change the sequence, the formula of the peptide or the mass on a mass spectrum.

Which mass confirms BPC-157 on an analytical report?

A BPC-157 identity result should match the free-peptide mass: 1419.53 g/mol average or 1418.70 Da monoisotopic (calculated). In positive electrospray the main ions are calculated at m/z 1419.71 for [M+H]+ and 710.36 for [M+2H]2+; the observed value for the sampled production run is the one printed on the report.

What is the legal status of BPC-157 in the US in 2026?

As of September 24, 2026, BPC-157 is not in the FDA's current Category 2 table: the FDA compounding page (content current as of April 22, 2026) lists it in the separate table of bulk drug substances nominated but withdrawn, after it had been added to Category 2 under the 503A interim policy on September 29, 2023. Those lists concern compounding. Pepta Labs lists BPC-157 as a research-use-only laboratory reference material for delivery to United States addresses only; the legal status guide covers research-use labelling.

Sources

• FDA compounding page holding the Category 2 table and the table headed "bulk drug substances nominated but withdrawn" (fda.gov); content current as of April 22, 2026; checked September 24, 2026.
• Internet Archive capture (April 27, 2025) of the same FDA page, content current as of September 27, 2024, for the 503A Category 2 entry dated September 29, 2023.
• PubChem compound record CID 9941957, including CAS Registry Number 137525-51-0 and the synonyms PL-14736 and PLD-116.
• FDA Global Substance Registration System, UNII 8ED8NXK95P.
• Pepta Labs listing values for sequence, formula, molecular weight, salt form, storage and vial quantity. Monoisotopic masses, ions, salt formula weights and deletion shifts on this page are calculated from the formula and sequence.

Where to order BPC-157

All products are supplied for laboratory research use only and are not for human or animal use.