RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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Brianna S.
✓ Verified Buyer
16 days ago
Product matched description and arrived quickly.
Mechanism of Action
Sermorelin (GRF 1-29) is the biologically active N-terminal fragment of endogenous GHRH. It binds pituitary GHRH receptors to trigger cAMP-PKA-mediated GH gene transcription and pulsatile release. Extensive safety data spanning decades.
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1
Approximately doubled 12-hour mean GH concentration in healthy elderly men
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2
Long-term administration increased lean body mass by 1.26 kg in older adults
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3
Preserves pituitary GH reserve and feedback sensitivity unlike exogenous GH
Effects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly men
PMID: 9005976
Vittone J, Blackman MR, et al.
— Metabolism (1997)
Nightly sermorelin injections doubled 12-hour mean GH concentration in healthy elderly men
Endocrine and metabolic effects of long-term administration of growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women
PMID: 9141536
Khorram O, Laughlin GA, Yen SSC
— Journal of Clinical Endocrinology and Metabolism (1997)
5-month treatment increased lean body mass by 1.26 kg and elevated IGF-1
Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?
PMID: 18046908
Walker RF
— Clinical Interventions in Aging (2006)
Sermorelin may be superior to exogenous GH because it preserves the natural GH feedback axis
Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency
PMID: 18031173
Prakash A, Goa KL
— BioDrugs (1999)
Review establishing sermorelin efficacy in increasing height velocity in GH-deficient children
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.0% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Sermorelin
What is Sermorelin?
Sermorelin (GHRH(1-29)) is a research-grade peptide supplied at 5mg/vial with ≥99.00% HPLC-verified purity. GHRH(1-29) for growth hormone release research.
What purity is your Sermorelin?
Our Sermorelin is verified at ≥99.00% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Sermorelin?
Store lyophilized Sermorelin at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Sermorelin?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Sermorelin third-party tested?
Yes. Every batch of Sermorelin is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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