RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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Sarah B.
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11 days ago
Everything looked correct and the packaging was clean.
Mechanism of Action
Epithalon (Epitalon, Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analogue of epithalamin from the pineal gland. It activates telomerase reverse transcriptase (hTERT) expression enabling telomere elongation, restores evening melatonin production, and modulates oxidative stress defense enzymes.
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1
Activated telomerase and induced telomere elongation in human somatic cells
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2
Extended maximum lifespan by 12.3% in mice while reducing spontaneous tumor incidence 6-fold
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3
Stimulated neurogenic differentiation markers 1.6-1.8 fold in stem cells
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells
PMID: 12937682
Khavinson VKh, Bondarev IE, Butyugov AA
— Bulletin of Experimental Biology and Medicine (2003)
Epithalon induced hTERT expression, telomerase activity, and telomere elongation in human fetal fibroblasts
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
PMID: 14501183
Anisimov VN, Khavinson VKh, et al.
— Biogerontology (2003)
Epitalon increased maximum lifespan by 12.3% and inhibited leukemia development 6-fold
AEDG peptide (Epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism
PMID: 32019204
Khavinson V, Diomede F, et al.
— Molecules (2020)
Epitalon increased neurogenic markers 1.6-1.8x in stem cells via histone binding
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.2% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Epithalon
What is Epithalon?
Epithalon (Epitalon) is a research-grade peptide supplied at 50mg/vial with ≥99.20% HPLC-verified purity. Tetrapeptide for telomerase and longevity research.
What purity is your Epithalon?
Our Epithalon is verified at ≥99.20% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Epithalon?
Store lyophilized Epithalon at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Epithalon?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Epithalon third-party tested?
Yes. Every batch of Epithalon is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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