RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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EK
Evan K.
✓ Verified Buyer
18 days ago
DSIP arrived intact and labeled clearly.
Mechanism of Action
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated from rabbit cerebral venous blood. It enhances delta-wave EEG through GABA-A receptor positive allosteric modulation, inhibits CRH release to reduce cortisol, and modulates circadian rhythm through suprachiasmatic nucleus signaling.
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1
Increased total sleep by 59% within 130 minutes of treatment in human volunteers
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2
Selectively enhanced deep slow-wave sleep without suppressing REM or causing morning sedation
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3
Significantly lowered chronic pain levels in 6 of 7 patients with migraine and headache disorders
Acute and delayed effects of DSIP on human sleep behavior
PMID: 6895513
Schneider-Helmert D, Gnirss F, et al.
— International Journal of Clinical Pharmacology Therapy and Toxicology (1981)
DSIP increased total sleep by 59% within 130 minutes with improved sleep efficiency
Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients: a double-blind study
PMID: 1299794
Bes F, Hofman W, et al.
— Neuropsychobiology (1992)
DSIP produced higher sleep efficiency and shorter sleep latency in chronic insomniacs
Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes
PMID: 6548970
Larbig W, Gerber WD, et al.
— European Neurology (1984)
DSIP significantly lowered pain levels in 6 of 7 patients with chronic migraine/headaches
Delta sleep-inducing peptide (DSIP): a still unresolved riddle
PMID: 16539679
Kovalzon VM, Strekalova TV
— Journal of Neurochemistry (2006)
Comprehensive review of DSIP role beyond sleep: endocrine regulation, thermoregulation, pain modulation
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.0% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about DSIP
What is DSIP?
DSIP (Delta Sleep-Inducing Peptide) is a research-grade peptide supplied at 5mg/vial with ≥99.00% HPLC-verified purity. Neuropeptide for sleep and stress research.
What purity is your DSIP?
Our DSIP is verified at ≥99.00% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store DSIP?
Store lyophilized DSIP at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on DSIP?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is DSIP third-party tested?
Yes. Every batch of DSIP is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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