RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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Jacob M.
✓ Verified Buyer
22 days ago
Order arrived safely and the seal was intact. Everything matched the page.
Mechanism of Action
Retatrutide (LY3437943) is a first-in-class triple GIP/GLP-1/glucagon receptor agonist. The glucagon component activates hepatic lipid oxidation, increases energy expenditure through thermogenesis, and promotes ketogenesis. Triple receptor engagement produces synergistic effects exceeding dual agonists.
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1
Phase 2: 24.2% mean weight loss at 12mg over 48 weeks — largest pharmacological weight loss reported
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2
Nearly 100% of participants at highest dose achieved >=5% weight loss
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3
Hepatic fat reduction of ~82% from baseline in liver fat sub-study
Triple-hormone-receptor agonist retatrutide for obesity - a phase 2 trial
PMID: 37366315
Jastreboff AM, Kaplan LM, et al.
— New England Journal of Medicine (2023)
Retatrutide produced up to 24.2% weight loss at 48 weeks in 338 participants
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes
PMID: 37385280
Rosenstock J, Frias JP, et al.
— Lancet (2023)
Superior glycemic control with up to 2.02% HbA1c reduction plus 16.9% weight loss in T2DM
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.2% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Retatrutide 10mg
What is Retatrutide 10mg?
Retatrutide 10mg (GLP-1/GIP/Glucagon Tri-Agonist) is a research-grade peptide supplied at 10mg/vial with ≥99.20% HPLC-verified purity. Triple-agonist peptide for metabolic research.
What purity is your Retatrutide 10mg?
Our Retatrutide 10mg is verified at ≥99.20% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Retatrutide 10mg?
Store lyophilized Retatrutide 10mg at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Retatrutide 10mg?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Retatrutide 10mg third-party tested?
Yes. Every batch of Retatrutide 10mg is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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