RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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AL
Ariana L.
✓ Verified Buyer
12 days ago
Arrived as described and packaged well. Would reorder.
DM
Dylan M.
✓ Verified Buyer
20 days ago
Fast shipping and proper sealing. Clean presentation.
Mechanism of Action
Melanotan-II is a synthetic cyclic heptapeptide alpha-MSH analogue with broad melanocortin receptor activity (MC1R-MC5R). Beyond melanogenesis via MC1R, MC3R/MC4R activation in the hypothalamus modulates appetite and sexual arousal. ~1000-fold greater potency than native alpha-MSH.
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1
Produced significant visible skin darkening at sub-milligram subcutaneous doses
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2
Initiated erections in 8 of 10 men with psychogenic ED in double-blind crossover study
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3
Served as parent compound from which PT-141 (bremelanotide) was developed
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
PMID: 8637402
Dorr RT, Lines R, et al.
— Life Sciences (1996)
MT-II produced tanning and spontaneous penile erection in first-in-human Phase I study
Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study
PMID: 9679884
Wessells H, Fuciarelli K, et al.
— Journal of Urology (1998)
MT-II initiated erections in 8 of 10 men with psychogenic ED
Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
PMID: 11018622
Wessells H, Levine N, et al.
— Urology (2000)
MT-II initiated erections in men with organic ED risk factors
Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II
PMID: 11035391
Wessells H, Hruby VJ, et al.
— International Journal of Impotence Research (2000)
MT-II led to erection in 17 of 20 men with increased sexual desire after 68% of doses
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.3% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Melanotan-II
What is Melanotan-II?
Melanotan-II (Cyclic MSH Analog) is a research-grade peptide supplied at 10mg/vial with ≥99.30% HPLC-verified purity. Cyclic MSH analog for tanning and sexual health research.
What purity is your Melanotan-II?
Our Melanotan-II is verified at ≥99.30% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Melanotan-II?
Store lyophilized Melanotan-II at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Melanotan-II?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Melanotan-II third-party tested?
Yes. Every batch of Melanotan-II is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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