RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
By using this site, you confirm you are 21+ and acknowledge these products are not FDA approved.
MT
Marcus T.
✓ Verified Buyer
15 days ago
Arrived cold packed and sealed properly. Good first order.
Mechanism of Action
NAD+ is the primary electron carrier in mitochondrial oxidative phosphorylation. It activates sirtuins (SIRT1-7) which regulate DNA repair, mitochondrial biogenesis, and stress responses. NAD+ tissue levels decline ~50% between ages 40 and 60.
-
1
12-month NMN administration suppressed age-associated weight gain and improved energy metabolism in aged mice
-
2
First human trial: NMN increased skeletal muscle insulin sensitivity in prediabetic women
-
3
Dose-dependent NAD+ increases and improved 6-minute walk test in multicenter RCT
Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice
PMID: 28068222
Mills KF, Yoshida S, et al.
— Cell Metabolism (2016)
12-month NMN suppressed age-associated body weight gain, enhanced energy metabolism, and improved insulin sensitivity
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
PMID: 33888596
Yoshino M, Yoshino J, et al.
— Science (2021)
10-week NMN (250mg/day) increased skeletal muscle insulin sensitivity in prediabetic women
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
PMID: 31685720
Irie J, Inagaki E, et al.
— Endocrine Journal (2020)
First-in-human study demonstrating oral NMN safety and effective metabolism
The efficacy and safety of beta-nicotinamide mononucleotide supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, dose-dependent clinical trial
PMID: 36482258
Yi L, Maier AB, et al.
— GeroScience (2023)
NMN at 300-900mg/day increased blood NAD+ dose-dependently and improved 6-minute walk test
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.5% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about NAD+ 500mg
What is NAD+ 500mg?
NAD+ 500mg (Nicotinamide Adenine Dinucleotide) is a research-grade peptide supplied at 500mg/vial with ≥99.50% HPLC-verified purity. NAD+ for cellular energy and longevity research.
What purity is your NAD+ 500mg?
Our NAD+ 500mg is verified at ≥99.50% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store NAD+ 500mg?
Store lyophilized NAD+ 500mg at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on NAD+ 500mg?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is NAD+ 500mg third-party tested?
Yes. Every batch of NAD+ 500mg is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
Related Geroprotection & Immunomodulation Peptides