RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
By using this site, you confirm you are 21+ and acknowledge these products are not FDA approved.
Mechanism of Action
Thymosin Alpha-1 (Thymalfasin, Zadaxin) is a 28-amino acid thymic peptide. It activates TLR2/TLR9 on dendritic cells, promotes T-cell priming, enhances CD4+/CD8+ maturation, increases NK cell cytotoxicity, and modulates Th1/Th2 balance. Approved in 35+ countries for hepatitis B and immune deficiency.
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1
Pivotal Phase III improved HBV seroconversion in chronic hepatitis B patients
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2
Review of 30+ trials (11,000+ subjects) found no severe adverse reactions
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3
Demonstrated survival benefit in severe sepsis when combined with standard of care
Thymosin alpha1 treatment of chronic hepatitis B: results of a phase III multicentre, randomized, double-blind and placebo-controlled study
PMID: 10607256
Mutchnick MG, Lindsay KL, et al.
— Journal of Viral Hepatitis (1999)
Pivotal Phase III establishing thymosin alpha-1 efficacy for chronic hepatitis B
Thymosin alpha 1: a comprehensive review of the literature
PMID: 33362999
Dominari A, Hathaway D, et al.
— World Journal of Virology (2020)
Comprehensive review confirming thymosin alpha-1 as well-tolerated immune modifier
Garaci E, Favalli C, et al.
— Annals of the New York Academy of Sciences (2007)
Demonstrated synergistic effects with interferons and chemotherapy in cancer models
Comprehensive review of the safety and efficacy of thymosin alpha 1 in human clinical trials
PMID: 38308608
Dinetz A, Lee E
— Alternative Therapies in Health and Medicine (2024)
Review of 30+ trials found no severe adverse reactions across 11,000+ subjects
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.1% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Thymosin Alpha-1
What is Thymosin Alpha-1?
Thymosin Alpha-1 (Immune Peptide) is a research-grade peptide supplied at 10mg/vial with ≥99.10% HPLC-verified purity. Thymic peptide for immune modulation research.
What purity is your Thymosin Alpha-1?
Our Thymosin Alpha-1 is verified at ≥99.10% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Thymosin Alpha-1?
Store lyophilized Thymosin Alpha-1 at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Thymosin Alpha-1?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Thymosin Alpha-1 third-party tested?
Yes. Every batch of Thymosin Alpha-1 is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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