RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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Natalie R.
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13 days ago
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Mechanism of Action
Selank is a synthetic heptapeptide combining immunomodulatory tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension. It modulates GABA-A receptor allosteric sites producing anxiolytic effects without sedation or dependence. Also enhances enkephalin levels. Approved in Russia for generalized anxiety disorder.
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Anxiolytic effects comparable to benzodiazepine medazepam but without sedation or dependence
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Affected expression of 45 of 84 genes related to GABAergic system functioning in frontal cortex
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Protected against ethanol-induced memory impairment by normalizing BDNF
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Reduced morphine withdrawal syndrome index by 39.6% after single injection
Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia
PMID: 18454096
Zozulia AA, Neznamov GG, et al.
— Zhurnal Nevrologii i Psikhiatrii (2008)
Selank showed anxiolytic effects comparable to medazepam with additional antiasthenic properties in 62 patients
Selank administration affects the expression of some genes involved in GABAergic neurotransmission
PMID: 26924987
Volkova A, Shadrina M, et al.
— Frontiers in Pharmacology (2016)
Selank affected 45 of 84 GABAergic genes suggesting anxiolytic action through GABA-A modulation
Selank, peptide analogue of tuftsin, protects against ethanol-induced memory impairment by regulating of BDNF content in the hippocampus and prefrontal cortex in rats
PMID: 31625062
Kolik LG, Nadorova AV, et al.
— Bulletin of Experimental Biology and Medicine (2019)
Selank prevented ethanol-induced memory disturbances while normalizing BDNF levels
Selank, a peptide analog of tuftsin, attenuates aversive signs of morphine withdrawal in rats
PMID: 36322304
Konstantinopolsky MA, Chernyakova IV, Kolik LG
— Bulletin of Experimental Biology and Medicine (2022)
Single Selank injection reduced total morphine withdrawal syndrome index by 39.6%
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.0% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about Selank
What is Selank?
Selank (TP-7 Peptide) is a research-grade peptide supplied at 10mg/vial with ≥99.00% HPLC-verified purity. Tuftsin analog for anxiolytic and nootropic research.
What purity is your Selank?
Our Selank is verified at ≥99.00% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store Selank?
Store lyophilized Selank at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on Selank?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is Selank third-party tested?
Yes. Every batch of Selank is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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