Peptide Research Library

BPC-157

Body Protection Compound

Regenerative Medicine & Tissue Engineering

BPC-157 is a synthetic pentadecapeptide derived from human gastric juice protein. It promotes healing through upregulation of the FAK-paxillin pathway and VEGF-mediated angiogen...

📄 5 studies 🔬 5 key findings

TB-500

Thymosin Beta-4 Fragment

Regenerative Medicine & Tissue Engineering

TB-500 (Thymosin Beta-4) is a 43-amino acid peptide that sequesters G-actin monomers to regulate actin polymerization, promoting cell migration and proliferation. It activates i...

📄 5 studies 🔬 5 key findings

SS-31

Elamipretide

Regenerative Medicine & Tissue Engineering

SS-31 (Elamipretide) is a synthetic tetrapeptide that selectively targets mitochondrial cardiolipin on the inner membrane. It stabilizes electron transport chain complexes, prev...

📄 5 studies 🔬 5 key findings

GHK-Cu

Copper Peptide Complex

Dermatological Science & Cutaneous Biology

GHK-Cu is a naturally occurring tripeptide-copper complex found in human plasma that declines with age. It stimulates collagen I, III, and elastin synthesis via TGF-beta signali...

📄 4 studies 🔬 4 key findings

KPV

Alpha-MSH Tripeptide

Dermatological Science & Cutaneous Biology

KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-MSH that retains potent anti-inflammatory activity without melanogenic effects. It inhibits NF-kB nuclear translocation, ...

📄 4 studies 🔬 4 key findings

Semaglutide 5mg

GLP-1 Receptor Agonist

Metabolic Regulation & Energy Homeostasis

Semaglutide is a long-acting GLP-1 receptor agonist with 94% homology to native GLP-1. A C-18 fatty diacid enables albumin binding and ~7-day half-life. It enhances glucose-depe...

📄 4 studies 🔬 4 key findings

Tirzepatide 15mg

GLP-1/GIP Dual Agonist

Metabolic Regulation & Energy Homeostasis

Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist. The GIP component enhances beta-cell insulin secretion and promotes fat oxidation, while GLP-1 activation pr...

📄 4 studies 🔬 4 key findings

Retatrutide 10mg

GLP-1/GIP/Glucagon Tri-Agonist

Metabolic Regulation & Energy Homeostasis

Retatrutide (LY3437943) is a first-in-class triple GIP/GLP-1/glucagon receptor agonist. The glucagon component activates hepatic lipid oxidation, increases energy expenditure th...

📄 2 studies 🔬 3 key findings

Cagrilintide 5mg

Amylin Analog

Metabolic Regulation & Energy Homeostasis

Cagrilintide is a long-acting amylin receptor agonist with fatty acid acylation for once-weekly dosing. It activates area postrema neurons for central appetite suppression, dela...

📄 2 studies 🔬 2 key findings

5-Amino-1MQ

NNMT Inhibitor

Metabolic Regulation & Energy Homeostasis

5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme overexpressed in adipose tissue. NNMT inhibition increases intracellular NAD+ availabi...

📄 3 studies 🔬 3 key findings

SLUPP-332 250mcg

ERRg Activator

Metabolic Regulation & Energy Homeostasis

SLU-PP-332 is a first-in-class synthetic pan-agonist of estrogen-related receptors (ERRalpha/beta/gamma) that mimics exercise pharmacologically. ERR activation upregulates mitoc...

📄 3 studies 🔬 3 key findings

Ipamorelin

Growth Hormone Secretagogue

Endocrinology & Somatotropic Signaling

Ipamorelin is a highly selective pentapeptide ghrelin receptor (GHS-R1a) agonist. Unlike other GH secretagogues, it stimulates GH release without affecting cortisol, prolactin, ...

📄 3 studies 🔬 3 key findings

CJC-1295 with DAC

GHRH Analog (DAC)

Endocrinology & Somatotropic Signaling

CJC-1295 with DAC is a synthetic GHRH(1-29) analogue modified with a maleimidopropionic acid linker enabling covalent albumin binding. This extends half-life from minutes to 6-8...

📄 1 studies 🔬 3 key findings

Tesamorelin

GHRH Analog

Endocrinology & Somatotropic Signaling

Tesamorelin is a stabilized GHRH(1-44) analogue with an N-terminal modification. FDA-approved as Egrifta for HIV-associated lipodystrophy, it specifically promotes visceral adip...

📄 4 studies 🔬 2 key findings

Sermorelin

GHRH(1-29)

Endocrinology & Somatotropic Signaling

Sermorelin (GRF 1-29) is the biologically active N-terminal fragment of endogenous GHRH. It binds pituitary GHRH receptors to trigger cAMP-PKA-mediated GH gene transcription and...

📄 4 studies 🔬 3 key findings

MOTS-C

Mitochondrial ORF

Metabolic Regulation & Energy Homeostasis

MOTS-c is a 16-amino acid mitochondrial-derived peptide encoded in the 12S rRNA gene — the first known mitochondrial-encoded peptide with hormonal function (mitokine). It activa...

📄 4 studies 🔬 3 key findings

Melanotan-I

Afamelanotide

Melanocortin Biology & Reproductive Science

Melanotan-I (Afamelanotide) is a synthetic linear alpha-MSH analogue that selectively activates MC1R on melanocytes, stimulating eumelanin production through cAMP-PKA-CREB-MITF ...

📄 3 studies 🔬 3 key findings

Melanotan-II

Cyclic MSH Analog

Melanocortin Biology & Reproductive Science

Melanotan-II is a synthetic cyclic heptapeptide alpha-MSH analogue with broad melanocortin receptor activity (MC1R-MC5R). Beyond melanogenesis via MC1R, MC3R/MC4R activation in ...

📄 4 studies 🔬 3 key findings

PT-141

Bremelanotide

Melanocortin Biology & Reproductive Science

PT-141 (Bremelanotide, Vyleesi) selectively activates MC3R and MC4R in the hypothalamus, producing sexual arousal through central dopaminergic pathways rather than peripheral va...

📄 4 studies 🔬 3 key findings

Semax

ACTH(4-7)-PGP

Neuropharmacology & Cognitive Enhancement

Semax is a synthetic heptapeptide analogue of ACTH(4-10) that enhances BDNF and NGF expression through TrkB receptor signaling, modulates serotonergic and dopaminergic systems, ...

📄 4 studies 🔬 3 key findings

Selank

TP-7 Peptide

Neuropharmacology & Cognitive Enhancement

Selank is a synthetic heptapeptide combining immunomodulatory tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro extension. It modulates GABA-A receptor allosteric sites producing anx...

📄 4 studies 🔬 4 key findings

DSIP

Delta Sleep-Inducing Peptide

Neuropharmacology & Cognitive Enhancement

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide first isolated from rabbit cerebral venous blood. It enhances delta-wave EEG through GABA-A receptor pos...

📄 4 studies 🔬 3 key findings

Epithalon

Epitalon

Geroprotection & Immunomodulation

Epithalon (Epitalon, Ala-Glu-Asp-Gly) is a synthetic tetrapeptide analogue of epithalamin from the pineal gland. It activates telomerase reverse transcriptase (hTERT) expression...

📄 3 studies 🔬 3 key findings

NAD+ 500mg

Nicotinamide Adenine Dinucleotide

Geroprotection & Immunomodulation

NAD+ is the primary electron carrier in mitochondrial oxidative phosphorylation. It activates sirtuins (SIRT1-7) which regulate DNA repair, mitochondrial biogenesis, and stress ...

📄 4 studies 🔬 3 key findings

Thymosin Alpha-1

Immune Peptide

Geroprotection & Immunomodulation

Thymosin Alpha-1 (Thymalfasin, Zadaxin) is a 28-amino acid thymic peptide. It activates TLR2/TLR9 on dendritic cells, promotes T-cell priming, enhances CD4+/CD8+ maturation, inc...

📄 4 studies 🔬 3 key findings

Kisspeptin

Metastin

Geroprotection & Immunomodulation

Kisspeptin is a family of peptides encoded by the KISS1 gene that bind GPR54 on GnRH neurons. Kisspeptin-GPR54 signaling serves as the master switch for the HPG axis, controllin...

📄 4 studies 🔬 3 key findings