RESEARCH USE ONLY: All products are for laboratory research purposes only. Not for human or animal consumption.
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Mechanism of Action
SLU-PP-332 is a first-in-class synthetic pan-agonist of estrogen-related receptors (ERRalpha/beta/gamma) that mimics exercise pharmacologically. ERR activation upregulates mitochondrial biogenesis, enhances fatty acid beta-oxidation, and increases oxidative muscle fiber composition.
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1
Increased running endurance in sedentary mice by inducing oxidative muscle fiber type switching
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2
Reduced obesity and improved glucose tolerance in diet-induced obese mice
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3
Ameliorated heart failure by enhancing cardiac fatty acid metabolism
Synthetic ERR agonist induces an ERR-dependent acute aerobic exercise response and enhances exercise capacity
PMID: 36988910
Billon C, Sitaula S, et al.
— ACS Chemical Biology (2023)
SLU-PP-332 increased mitochondrial function, type IIa oxidative muscle fibers, and exercise endurance
Billon C, Schoepke E, et al.
— Journal of Pharmacology and Experimental Therapeutics (2024)
SLU-PP-332 increased energy expenditure, decreased fat mass, and improved glucose tolerance in obese mice
Novel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function
PMID: 37961903
Xu W, Billon C, et al.
— Circulation (2024)
Pan-ERR agonists improved ejection fraction and reduced fibrosis in heart failure models
Storage
Store lyophilized peptide at -20°C for long-term stability. Reconstituted solution should be stored at 2-8°C and used within 30 days. Avoid repeated freeze-thaw cycles.
Reconstitution
Reconstitute with bacteriostatic water (0.9% benzyl alcohol). Add solvent slowly down the side of the vial. Do not shake; gently swirl until dissolved.
Purity & Testing
Purity verified at ≥99.0% by HPLC. Each lot includes Certificate of Analysis with mass spectrometry confirmation and endotoxin testing.
Research Use Only
This product is intended for laboratory research purposes only. Not for human or animal consumption. Not FDA-approved for therapeutic use. Handle according to institutional biosafety protocols.
Frequently Asked Questions about SLUPP-332 250mcg
What is SLUPP-332 250mcg?
SLUPP-332 250mcg (ERRg Activator) is a research-grade peptide supplied at 30ct · 250mcg with ≥99.00% HPLC-verified purity. ERRg activator for mitochondrial biogenesis research.
What purity is your SLUPP-332 250mcg?
Our SLUPP-332 250mcg is verified at ≥99.00% purity by High-Performance Liquid Chromatography (HPLC). Each lot includes a Certificate of Analysis with mass spectrometry confirmation and endotoxin testing results.
How should I store SLUPP-332 250mcg?
Store lyophilized SLUPP-332 250mcg at -20°C for optimal long-term stability. After reconstitution with bacteriostatic water, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles to maintain peptide integrity.
Do you offer bulk discounts on SLUPP-332 250mcg?
Yes. We offer tiered pricing: 3-vial packs include a 7% discount and 5-vial packs include a 14% discount. All multi-vial options are available on this product page above.
Is SLUPP-332 250mcg third-party tested?
Yes. Every batch of SLUPP-332 250mcg is independently tested by third-party laboratories using HPLC and mass spectrometry. Certificate of Analysis available upon request. All products are manufactured under ISO-compliant conditions.
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