Where to Buy CJC-1295 no DAC in 2026: Sizes, Purity & Verification

CJC-1295 no DAC, also listed as Modified GRF (1-29) or Mod GRF 1-29, is a synthetic linear 29-residue peptide amide (C152H252N44O42, 3367.95 g/mol). Pepta Labs lists it as a single 5 mg vial at 99.1% reported RP-HPLC purity. The "no DAC" qualifier is the first thing to check, because CJC-1295 with DAC is a different, heavier molecule. This guide covers the chemistry, the listing, the report, storage and FDA status in 2026.

What Is CJC-1295 no DAC?

GRF stands for growth hormone-releasing factor, and GRF(1-29)-NH2 is the 29-residue amide better known as sermorelin. CJC-1295 no DAC is that sequence with four substitutions: D-alanine at position 2, glutamine at 8, alanine at 15 and leucine at 27. The last replaces methionine, so the formula contains no sulfur, whereas sermorelin is C149H246N44O42S (3357.93 g/mol, CAS 86168-78-7). The 10 g/mol difference is small but measurable by mass spectrometry.

"No DAC" and "with DAC" are different molecules

DAC stands for Drug Affinity Complex. CJC-1295 with DAC is a 30-residue construct in which an additional C-terminal lysine carries a maleimidopropionyl group; its formula is C165H269N47O46 and its mass about 3647.2 Da (PubChem CID 91971820). The no-DAC form has neither the extra lysine nor the maleimide and is roughly 279 Da lighter. PubChem's synonym list for CID 56841945 mixes both names, so judge a listing by its formula and observed mass, never by name alone. See CAS numbers and molecular weights.

How Pepta Labs Lists CJC-1295 no DAC

The listing is a lyophilized powder in a sealed glass vial. Reported reversed-phase HPLC purity of 99.1% is shown on the product page, identity is confirmed by mass spectrometry, and the production-run report is sent by email on request, with no account or minimum order. Salt form (trifluoroacetate or acetate) and net peptide content are stated on the report. With three arginine and two lysine residues plus the N-terminal amine, the peptide carries several counter-ions per molecule, so the gap between label quantity and net peptide content is wider than for a short peptide (see TFA vs acetate and net peptide content). Related listings are on the category page.

How to Verify a CJC-1295 no DAC Listing

What an HPLC/MS report shows

For a 29-residue peptide the HPLC chromatogram is the main purity evidence: deletion sequences, truncated chains and incompletely deprotected residues elute close to the main peak, and purity is the main peak's share of total area. Mass spectrometry confirms that the main peak has the mass of the full-length sequence. A peptide this size carries several charges in electrospray, so the raw spectrum shows multiply charged ions that the laboratory deconvolutes to one mass. See HPLC vs mass spec.

What it does not show

• Peak-area purity excludes counter-ion and water, so it is not the same number as net peptide content.
• The D-configuration of alanine at position 2 is invisible to RP-HPLC and MS; the L-Ala2 peptide has the same mass. Only chiral amino-acid analysis resolves it.
• A single-mass result can hide deamidation (a +1 Da change at any of the three glutamine residues) unless high-resolution data are reported.
• Neither test is a sterility or endotoxin result.

Production-run report vs lot-specific COA

Pepta Labs supplies the independent laboratory's report for the sourced production run, the synthesized batch the vials were filled from. A lot-specific certificate of analysis is issued per fill lot after vialling. Both are acceptable if the identifier on the vial matches the document and the document names the laboratory, method, column and test date. The COA verification guide gives a field-by-field checklist.

Comparing observed mass to theoretical mass

The average molecular weight is 3367.95 and the monoisotopic mass 3365.89 Da; a report may quote either. In electrospray the main ions fall near m/z 1123.7 ([M+3H]³⁺), 843.0 ([M+4H]⁴⁺) and 674.6 ([M+5H]⁵⁺). A deconvoluted mass within about 1 Da of 3367.9 (average) or 3365.9 (monoisotopic) is consistent with the listing. Two neighbours must be ruled out: sermorelin at 3357.9 (10 Da lower, and containing sulfur) and CJC-1295 with DAC at about 3647 (279 Da higher). A report showing 3647 under a "no DAC" label describes the wrong material.

Storage and Shipping

CJC-1295 no DAC ships as a lyophilized powder at ambient temperature; a few days in transit without cold packs is normal for the dry solid. On arrival, refrigerate sealed vials at 2-8 C or move them to -20 C for long-term storage. Keep the vial sealed and dry, protected from light. The solid is white to off-white. Most orders ship the next business day with free US shipping.

US Regulatory Status in 2026

CJC-1295 is not a controlled substance; its FDA position concerns pharmacy compounding under sections 503A and 503B, not laboratory sale. FDA's list of bulk drug substances that may present significant safety risks (Category 2 under the interim policies), updated 22 April 2026, no longer shows CJC-1295 in the active Category 2 table. It appears under "bulk drug substances nominated but withdrawn", meaning its nomination was withdrawn by the nominators. FDA's entry uses the bare name "CJC-1295" and does not distinguish the DAC and no-DAC forms. Neither placement governs sale as a research chemical with research-use-only labelling. Status is summarised at peptide legal status 2026 and FDA Category 2 peptides 2026.

Frequently Asked Questions

How does CJC-1295 no DAC differ from sermorelin?

Both are 29-residue peptide amides based on GRF(1-29). CJC-1295 no DAC carries D-Ala2, Gln8, Ala15 and Leu27. Because Leu replaces Met27, its formula C152H252N44O42 contains no sulfur; sermorelin is C149H246N44O42S, 3357.93 g/mol, CAS 86168-78-7.

Is CJC-1295 no DAC the same as CJC-1295 with DAC?

No. The DAC form is a 30-residue construct with an extra lysine bearing a maleimidopropionyl group (C165H269N47O46, about 3647.2 Da). The no-DAC form is the 29-residue peptide amide at 3367.95 g/mol; the observed mass on the report tells them apart.

Why does the product page show no CAS number?

The registry number commonly cited for the free peptide, 863288-34-0, has not been confirmed against this listing, so it is not displayed. Formula, molecular weight and the mass-spectrometry result on the report identify the material without it.

What does Modified GRF (1-29) mean?

It is the descriptive name for the same molecule: GRF(1-29)-NH2 modified at positions 2, 8, 15 and 27. Listings under either name should show C152H252N44O42 and 3367.95 g/mol.

Where to Buy CJC-1295 no DAC

All products are supplied for laboratory research use only and are not for human or animal use.